Monovar: single-nucleotide variant detection in single cells - Nature.com

Nature.com
Monovar: single-nucleotide variant detection in single cells
Nature.com
Current variant callers are not suitable for single-cell DNA sequencing, as they do not account for allelic dropout, false-positive errors and coverage nonuniformity. We developed Monovar (https://bitbucket.org/hamimzafar/monovar), a statistical method ...y más »