Week 3 NFL odds, picks, predictions: Computer model backs Lions and 49ers
22-09-2026 15:34 via cbssports.com

Week 3 NFL odds, picks, predictions: Computer model backs Lions and 49ers

SportsLine's advanced model has simulated every game in the Week 3 NFL schedule 10,000 times and locked in its NFL best bets today
Read more »

NFL news



What to do with seven start-sit decisions you might be dreading
What to do with seven start-sit decisions you might be dreading
Week 3 NFL QB Power Rankings: Dak Prescott into top five; Aaron Rodgers continues to tank
Week 3 NFL QB Power Rankings: Dak Prescott into top five; Aaron Rodgers continues to tank
💍 Ranking the top 10 players without a Super Bowl ring
💍 Ranking the top 10 players without a Super Bowl ring
Use DraftKings promo code to get $150 in bonus bets by targeting Yankees-Rays, NFL, MLB betting on Wednesday
Use DraftKings promo code to get $150 in bonus bets by targeting Yankees-Rays, NFL, MLB betting on Wednesday
Panic meter for every 0-2 team: Texans have been here before, Commanders on downward spiral
Panic meter for every 0-2 team: Texans have been here before, Commanders on downward spiral
2026 Week 3 NFL odds, lines, schedule, start times: Picks, predictions for Falcons-Packers, every other game
2026 Week 3 NFL odds, lines, schedule, start times: Picks, predictions for Falcons-Packers, every other game
Ranking MVP candidates after Week 2: Josh Allen takes early lead, but a RB not too far behind
Ranking MVP candidates after Week 2: Josh Allen takes early lead, but a RB not too far behind
Week 3 NFL betting odds, lines, totals, spreads, for all 16 games, including Ravens-Cowboys, Rams-Broncos
Week 3 NFL betting odds, lines, totals, spreads, for all 16 games, including Ravens-Cowboys, Rams-Broncos
Matchup rankings for Week 3: McConkey, Purdy among players to upgrade
Matchup rankings for Week 3: McConkey, Purdy among players to upgrade
Panic level for Giants, Bears amid rash of QB injuries; MLB postseason scenarios as Rays clinch AL East
Panic level for Giants, Bears amid rash of QB injuries; MLB postseason scenarios as Rays clinch AL East
Use BetMGM bonus code CBSSPORTS to get $1,500 bonus bets by targeting Yankees-Rays, NFL, MLB betting Wednesday
Use BetMGM bonus code CBSSPORTS to get $1,500 bonus bets by targeting Yankees-Rays, NFL, MLB betting Wednesday
NFL Week 3 picks, odds: Josh Allen furthers Chargers free fall, Saints stay hot in home opener
NFL Week 3 picks, odds: Josh Allen furthers Chargers free fall, Saints stay hot in home opener
Panthers RB Jonathon Brooks headed to IR, Austin Ekeler scheduled for workout
Panthers RB Jonathon Brooks headed to IR, Austin Ekeler scheduled for workout
Two star QBs hurt, a near upset and a surprising win: Breaking down Week 2
Two star QBs hurt, a near upset and a surprising win: Breaking down Week 2
Desktop versie