Patriots vs. Bills odds, picks, prediction, spread: NFL Week 4 start time, betting preview, best bets
04-10-2026 14:10 via cbssports.com

Patriots vs. Bills odds, picks, prediction, spread: NFL Week 4 start time, betting preview, best bets

Here's everything bettors need to know about the crucial early AFC East showdown as the Bills host the Patriots at New Highmark Stadium on Sunday
Read more »

NFL news



Jets snag 1st interception in 21 games, snapping record drought
Jets snag 1st interception in 21 games, snapping record drought
Eagles RB Barkley won't return vs. Rams due to hamstring injury
Eagles RB Barkley won't return vs. Rams due to hamstring injury
Saquon Barkley injury: Eagles RB ruled out after injuring hamstring vs. Rams
Saquon Barkley injury: Eagles RB ruled out after injuring hamstring vs. Rams
Bengals' Ja'Marr Chase questionable to return after entering concussion evaluation vs. Jaguars
Bengals' Ja'Marr Chase questionable to return after entering concussion evaluation vs. Jaguars
Odell Beckham Jr. addresses Giants cutting him: 'I shoulda known better'
Odell Beckham Jr. addresses Giants cutting him: 'I shoulda known better'
Saquon Barkley injury: Eagles running back questionable to return after exiting vs. Rams
Saquon Barkley injury: Eagles running back questionable to return after exiting vs. Rams
Reid ranks the top 50 prospects in the 2027 NFL draft class: Smith at No. 1?
Reid ranks the top 50 prospects in the 2027 NFL draft class: Smith at No. 1?
NFL Week 4 questions, takeaways: Colts defeat the Commanders in London
NFL Week 4 questions, takeaways: Colts defeat the Commanders in London
Bears RB Kyle Monangai leads NFL Week 4's most fashionable arrivals
Bears RB Kyle Monangai leads NFL Week 4's most fashionable arrivals
🍼 'Upgraded to mom and dad': Michael Penix Jr., wife expecting first child
🍼 'Upgraded to mom and dad': Michael Penix Jr., wife expecting first child
Travis Kelce closing in on NFL history, could climb to No. 5 on all-time receptions list vs. Raiders
Travis Kelce closing in on NFL history, could climb to No. 5 on all-time receptions list vs. Raiders
NFL draft risers, notes off Saturday's college games: Could Jeremiah Smith go No. 1 in April?
NFL draft risers, notes off Saturday's college games: Could Jeremiah Smith go No. 1 in April?
Could the NFL scheduling formula undergo a massive change? Jerry Jones hints at one possible future tweak
Could the NFL scheduling formula undergo a massive change? Jerry Jones hints at one possible future tweak
Mariota ruled out as Commanders turn to 7th-round rookie at QB
Mariota ruled out as Commanders turn to 7th-round rookie at QB
Desktop versie