Targeting CD4 to Treat HIV

By Meaghan Lee CallaghanThere are integrase inhibitors, there is a capsid inhibitor, and there is ibalizumab-uiyk (Trogarzo, TaiMed Biologics), a CD4-directed post-attachment HIV-1 inhibitor.Although ibalizumab is FDA-approved for people with multidrug-resistant HIV who have failed other treatment options, TaiMed Biologics has a new drug combination using the same mechanism but that company CEO Jimmy Chang, PhD, said he hopes will apply to the larger population of people living with HIV.Dr. Chan