11-10-2026 21:58 via medpagetoday.com

And It's Back to the Drawing Board for PDE9 Inhibition in Heart Failure

(MedPage Today) -- PHOENIX--The development of a PDE9 inhibitor for heart failure hit a major roadblock, as two phase II placebo-controlled trials were suspected of having tested the wrong dose.
In both heart failure with reduced ejection...
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